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Saxenda Vials (Liraglutide)

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Description

General Information

Saxenda (liraglutide injection) is a glucagon-like peptide-1 (GLP-1) receptor agonist. GLP-1 is a physiological regulator of appetite and calorie intake, and the GLP-1 receptor is present in several areas of the brain involved in appetite regulation. purchase saxenda

Saxenda is specifically indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obese), or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g.,hypertension, type 2 diabetes mellitus, or dyslipidemia).

Saxenda is supplied as a solution for subcutaneous administration. The recommended dose of Saxenda is 3 mg daily. Administer at any time of day, without regard to the timing of meals. Dosing should be initiated at 0.6 mg per day for one week. Increase the dose in weekly intervals until a dose of 3 mg is reached. Saxenda should be injected subcutaneously in the abdomen, thigh or upper arm. The injection site and timing can be changed without dose adjustment.

Study Results Saxenda:

For Study 1 and Study 2, the primary efficacy parameters were mean percent change in body weight and the percentages of patients achieving greater than or equal to 5% and 10% weight loss from baseline to week 56. For Study 3, the primary efficacy parameters were mean percent change in body weight from randomization to week 56, the percentage of patients not gaining more than 0.5% body weight from randomization to week 56, and the percentage of patients achieving greater than or equal to 5% weight loss from randomization to week 56. After 56 weeks, treatment with Saxenda resulted in a statistically significant reduction in weight compared with placebo. Statistically significantly greater proportions of patients treated with Saxenda achieved 5% and 10% weight loss than those treated with placebo. In Study 3, statistically significantly more patients randomized to Saxenda than placebo had not gained more than 0.5% of body weight from randomization to week 56.

Side Effects Saxenda: purchase saxenda

Adverse effects associated with the use of Saxenda may include, but are not limited to, the following:

nausea
hypoglycemia
diarrhea
constipation
vomiting
headache
decreased appetite
dyspepsia
fatigue
dizziness
abdominal pain
increased lipase

Liraglutide causes thyroid C-cell tumors at clinically relevant exposures in both genders of rats and mice. It is unknown whether Saxenda causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans, as the human relevance of liraglutide-induced rodent thyroid C-cell tumors has not been determined. Saxendais contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Additional information

QTY

16 pen injector 3mg/0,5ml (18mg/3ml), 2 pen injector 3 mg/0,5ml (18mg/3ml), 4 pen injector 3mg/0,5ml (18mg/3ml), 8 pen injector 3mg/0,5ml (18mg/3ml)

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